The complexity of tourism products and the diversification of service organization demand to build tourist supply chain, which realizes the cooperation between the organizations to better meet the needs of tourists. Based on literature research in tourist supply chain, the paper puts forward that the construction of tourism supply chain is closely related to the environment of the tourism industry. The current China’s tourism industry is facing new change of market environment including mass tourism, information technology, environmental capacity, tourism destination, and market environment affects the structure of tourism supply chain and the core enterprise. For the influence of tourism destination on tourism activities and public service, establishing tourism destination as the core enterprise of tourist supply chain. Eventually the paper designs the Structure model and function model of tourist supply chain based on tourism destination, which hopes to promote the sustainable development of China’s tourism industry by fostering and practice tourism supply chain.