The European economic crisis on the euro zone requires us to reconsider the effect of the monetary integration policy. This article is based on the endogenous growth model (RBR) of the innovative elements to simulate the economic behavior of the euro zone with the member countries in the monetary integration, and by using the economic related data we estimate the dynamic policy impact. The results show that: the monetary integration will widen the gap between the different countries within the zone. In the case of good external economic environment with the capital adequacy, the monetary integration will promote the economic development of various countries and the gap will be narrowed; when the external economic environment is deteriorating with the capital shortage, the difference will be greater and the economic differentiation among countries will increase. Accordingly, to select appropriate integration policies, protect and support strategic industries, and enhance their economic strength are important prerequisites for regional cooperation and integration.