Aiming at the characteristics of agro-product supply chain, this study builds a research model with supply chain quality integration(SCQI) as the antecedent variable, agro-product quality safety performance(AQSP) as the mediating variable and financial performance(FP) as the dependent variable, and empirically analyzes the impact of SCQI on financial performance, and assesses the moderating effect of social co-regulation(SCR). The findings reveal that the internal quality integration(IQI) has a positive impact on the supplier quality integration(SQI) and customer quality integration(CQI), and the IQI,CQI and SQI all have a positive impact on AQSP and then on FP. However, compared with IQI and CQI, SQI has a greater impact on AQSP. The AQSP plays a partial mediation role in the impact of SCQI on FP. In addition, this study indicates that the SCR positively moderates the relationship between IQI and AQSP, as well as SQI and AQSP. That is, the improvement of SCR is conducive to enhancing the effect of IQI and SQI on AQSP respectively.