In the face of enterprise non-ethical behavior, the reason for employees’ silent tolerance is receiving increasing attention in recent years. Focusing on the specific situation of self-interest ethical climate, using a cross-level approach, this article explores the effects of ethical relief on employees’ silent tolerance under different attribution situations. The research finds that the ethical relief (attribution) plays a completely mediating role between self-interest ethic atmosphere and employees’ silence in the face of enterprise non-ethical issues. Moral disengagement plays a mediating role between self-interest ethics and employee silence. The power distance plays a negative role between ethical relief and employee silence. The research shows the reason for employees’ choice of silent tolerance in the face of non-ethical problems depends on the self-interest ethical atmosphere of the enterprise and the meaning construction of individual ethical relief. This paper is of theoretical and practical value in revealing the problem of employees’ choice of silence under the enterprise non-ethical behavior.